Invitrogen™ Cathepsin V Monoclonal Antibody (182021)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA523928

Catalog No. PIMA523928

Description

In direct ELISAs and Western blots, no cross-reactivity with recombinant human Cathepsin B, C, F, L, O, S, or Z is observed. This antibody specifically identifies the pro form but not the active form of Cathepsin V in Western blots. Reconstitute at 0.5 mg/mL in sterile PBS.

Cathepsin V (CTSU, CTSV, CATL2, cathepsin U, cathepsin L2) is a lysosomal cysteine proteinase that influences corneal physiology, and mediates degradation of invariant chain in human thymus. Cathepsin V is present in corneal epithelium, activated macrophages, and colorectal and breast carcinomas. A 1.8-kb mRNA to Cathepsin V is present in normal human thymus and testis. Cathepsin V is a member of the peptidase C1 family. Cysteine proteinases are synthesized as preproenzymes, which are processed to the corresponding proenzymes. The proenzymes are either targeted to the lysosome or continue along the cellular secretory route.

Specifications

• Antigen: Cathepsin V
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: O60911
• Gene Symbols: CTSV
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Cathepsin V Val18-Val334.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunoprecipitation, Western Blot
• Clone: 182021
• Conjugate: Unconjugated
• Gene: CTSV
• Gene Alias: Cathepsin L2; cathepsin L2, preproprotein; cathepsin U; Cathepsin V; CATL2; CTSL2; CTSU; CTSV; PRO305; UNQ268; UNQ268/PRO305
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 1515
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized