Invitrogen™ Cathepsin V Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537426

Catalog No. PIPA537426

Description

This antibody detects endogenous protein at a molecular weight of 37 kDa. Purity is >95% by SDS-PAGE.

Cathepsin V (CTSU, CTSV, CATL2, cathepsin U, cathepsin L2) is a lysosomal cysteine proteinase that influences corneal physiology, and mediates degradation of invariant chain in human thymus. Cathepsin V is present in corneal epithelium, activated macrophages, and colorectal and breast carcinomas. A 1.8-kb mRNA to Cathepsin V is present in normal human thymus and testis. Cathepsin V is a member of the peptidase C1 family. Cysteine proteinases are synthesized as preproenzymes, which are processed to the corresponding proenzymes. The proenzymes are either targeted to the lysosome or continue along the cellular secretory route.

Specifications

• Antigen: Cathepsin V
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CTSV
• Gene Alias: Cathepsin L2; cathepsin L2, preproprotein; cathepsin U; Cathepsin V; CATL2; CTSL2; CTSU; CTSV; PRO305; UNQ268; UNQ268/PRO305
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1515
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O60911
• Gene Symbols: CTSV
• Immunogen: Synthetic peptide corresponding to amino acids 91-140 of human Cathepsin L2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG