Invitrogen™ Cathepsin V Polyclonal Antibody

Catalog No.	Quantity
PIPA547061	100 μg

Catalog No. PIPA547061 Supplier Invitrogen™ Supplier No. PA547061

Description

Goat Polyclonal Antibody

In direct ELISAs, approximately 15% cross-reactivity with recombinant human (rh) Cathepsin C is observed and less than 5% cross-reactivity with rhCathepsin A, rhCathepsin D, rhCathepsin X/Z/P, rhCathepsin S, and rhCathepsin L is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Cathepsin V (CTSU, CTSV, CATL2, cathepsin U, cathepsin L2) is a lysosomal cysteine proteinase that influences corneal physiology, and mediates degradation of invariant chain in human thymus. Cathepsin V is present in corneal epithelium, activated macrophages, and colorectal and breast carcinomas. A 1.8-kb mRNA to Cathepsin V is present in normal human thymus and testis. Cathepsin V is a member of the peptidase C1 family. Cysteine proteinases are synthesized as preproenzymes, which are processed to the corresponding proenzymes. The proenzymes are either targeted to the lysosome or continue along the cellular secretory route.

Specifications

• Antigen: Cathepsin V
• Applications: Immunohistochemistry (Paraffin), Neutralization, Western Blot
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 5% trehalose and No Preservative
• Gene: CTSV
• Gene Accession No.: O60911
• Gene Alias: Cathepsin L2; cathepsin L2, preproprotein; cathepsin U; Cathepsin V; CATL2; CTSL2; CTSU; CTSV; PRO305; UNQ268; UNQ268/PRO305
• Gene Symbols: CTSV
• Host Species: Goat
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Cathepsin V Val18-Val334.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1515
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG