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CATSPER Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501989930
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100 μL
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50-198-9930 100 μL
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Catalog No. 50-198-9930 Supplier Bioss Supplier No. BS23327R
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Description

Rabbit Polyclonal Antibody

Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials; it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH.

Specifications

Antigen CATSPER
Applications Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation TBS with 1% BSA, 50% glycerol and 0.03% Proclin 300; pH
Gene CATSPER1
Gene Accession No. Q8NEC5
Gene Alias cation channel of sperm 1; cation channel sperm associated 1; Cation channel sperm-associated protein 1; cation channel, sperm associated 1; Catsper; CATSPER1; hCatSper; KSper; sperm ion channel; sperm protein CATSPER1; sperm-associated cation channel 1; SPGF7
Gene Symbols CATSPER1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from mouse CATSPER.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117144
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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