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Invitrogen™ CaV1.3 Monoclonal Antibody (S48)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA527716
Description
1 μg/mL of MA5-27716 was sufficient for detection of Cav1.3 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 250kDa. No cross-reactivity against Cav1.2.
CACNA1D is also known as PASNA, SANDD or Cav1. 3. Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene.
Specifications
CaV1.3 | |
Monoclonal | |
1 mg/mL | |
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4 | |
P27732, Q01668, Q99246 | |
CACNA1D | |
Fusion protein amino acids 859-875 of rat Cav1.3. | |
100 μg | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG2a κ |
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry, Microarray | |
S48 | |
Unconjugated | |
CACNA1D | |
8430418G19Rik; brain class D; C79217; Cach3; Cacn4; CACNA 1D; CACNA1D; Cacnl1a2; calcium channel alpha-1 subunit; Calcium channel, L type, alpha-1 polypeptide isoform 2; Calcium channel, L type, alpha-1 polypeptide, isoform 2; calcium channel, neuroendocrine/brain-type, alpha 1 subunit; calcium channel, voltage-dependent, L type, alpha 1D subunit; calcium voltage-gated channel subunit alpha1 D; Cav1.3; CaV1.3alpha1; Cchl1a; CCHL1A2; D-LTCC; PASNA; Rat brain class D; RBD; SANDD; voltage-dependent calcium channel subunit alpha1D; voltage-dependent L-type calcium channel subunit alpha-1D; voltage-gated calcium channel alpha 1 subunit; voltage-gated calcium channel alpha subunit Cav1.3; voltage-gated calcium channel pore forming subunit CaV1.3alpha1 IVS3-IVS4 extracellular linker; voltage-gated calcium channel subunit alpha Cav1.3 | |
Mouse | |
Protein G | |
RUO | |
12289, 29716, 776 | |
-20°C | |
Liquid |
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