CAV1 Mouse anti-Human, Mouse, Clone: OTI2C4, lyophilized, TrueMAB™

Catalog No.	Quantity
50-167-0987	100 μg

Catalog No. 50-167-0987 Supplier OriGene Supplier No. CF812677

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation. It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.

Specifications

• Antigen: CAV1
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI2C4
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: CAV1
• Gene Accession No.: P49817, Q03135
• Gene Alias: BSCL3, CGL3, LCCNS, MSTP085, PPH3, VIP21
• Gene Symbols: Cav1
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 2-104 of human CAV1 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 12389, 857
• Target Species: Human, Mouse
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1