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CAV1 (phospho Y14) Rabbit anti-Human, Mouse, Rabbit, Polyclonal , Abnova™

Catalog No. 89956741 Shop All Abnova Corporation Products
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100 μL
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89-956-741 100 μL
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Catalog No. 89-956-741 Supplier Abnova Corporation Supplier No. PAB29603
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human CAV1.

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene. [provided by RefSeq]

Specifications

Antigen CAV1 (phospho Y14)
Applications Immunofluorescence, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of human CAV1.
Dilution Immunofluorescence (1:100-1:200) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
Formulation In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Alias BSCL3/CAV/CGL3/MSTP085/VIP21
Gene Symbols CAV1
Host Species Rabbit
Immunogen A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y14 of human CAV1.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 857
Test Specificity CAV1 (phospho Y14) polyclonal antibody detects endogenous level of CAV1 only when phosphorylated at tyrosine 14.
Target Species Human, Mouse, Rabbit
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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