Invitrogen™ CaV3.1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550635

Catalog No. PA550635

Description

The antibody detects endogenous levels of total CACNA1G protein.

Voltage-dependent Ca2+ channels mediate Ca2+ entry into excitable cells in response to membrane depolarization, and they are involved in a variety of Ca2+-dependent processes, including muscle contraction, hormone or neurotransmitter release and gene expression. Calcium channels are highly diverse, multimeric complexes composed of an alpha-1 subunit, an intracellular beta subunit, a disulfide linked alpha-2/delta subunit and a transmembrane gamma subunit. Ca2+ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types. T-type Ca2+ currents are activated and inactivated more rapidly and at more negative membrane potentials than other Ca2+ current types. T-type Ca2+ channels enhance odor sensitivity by lowering the threshold of spike generation in olfactory receptor cells (ORCs).

Specifications

• Antigen: CaV3.1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CACNA1G
• Gene Alias: [a]1G; a1G; alpha-1G; Ca(V)T.1; CACNA1G; calcium channel, voltage-dependent, T type, alpha 1G subunit; calcium voltage-gated channel subunit alpha1 G; CaV T1; Cav3 1; cav3 1c; Cav3.1; Cav3.1c; Cav3.1d; KIAA1123; MGC117234; mKIAA1123; NBR13; SCA42; voltage-dependent calcium channel alpha 1G subunit, isoform 11; voltage-dependent T-type calcium channel alpha 1G subunit; voltage-dependent T-type calcium channel subunit alpha-1G; Voltage-gated calcium channel subunit alpha Cav3.1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8913
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1.9 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: O43497
• Gene Symbols: CACNA1G
• Immunogen: Synthetic peptide corresponding to residues near the C terminal of human calcium channel, voltage-dependent, T type, alpha 1G subunit.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG