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Invitrogen™ CaV3.2 Polyclonal Antibody
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Catalog No. PIPA5106771
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PIPA5106771 100 μL
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Catalog No. PIPA5106771 Supplier Invitrogen™ Supplier No. PA5106771
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CACNA1H.

This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE).
TRUSTED_SUSTAINABILITY

Specifications

Antigen CaV3.2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CACNA1H
Gene Accession No. O88427, O95180, Q9EQ60
Gene Alias A1H-b; alpha13.2; CACNA1H; CACNA1HB; calcium channel alpha13.2 subunit; calcium channel, voltage-dependent, T type, alpha 1H subunit; calcium channel, voltage-dependent, T type, alpha 1Hb subunit; calcium voltage-gated channel subunit alpha1 H; Cav3.2; ECA6; EIG6; FLJ90484; Low-voltage-activated calcium channel alpha1 3.2 subunit; low-voltage-activated calcium channel alpha13.2 subunit; MNCb-1209; T-type Cav3.2; voltage dependent t-type calcium channel alpha-1H subunit; voltage-dependent T-type calcium channel subunit alpha-1H; voltage-gated calcium channel alpha subunit Cav3.2; voltage-gated calcium channel alpha subunit CavT.2; voltage-gated calcium channel subunit alpha Cav3.2
Gene Symbols CACNA1H
Host Species Rabbit
Immunogen A synthesized peptide derived from human CACNA1H(Accession O95180), corresponding to amino acid residues E570-G620.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114862, 58226, 8912
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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