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Invitrogen™ Caveolin 1 Monoclonal Antibody (7C8)
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Catalog No. 01676574
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100 μg
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Catalog No. Quantity
01-676-574 100 μg
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Catalog No. 01-676-574 Supplier Invitrogen™ Supplier No. MA140241
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Description

Mouse Monoclonal Antibody

MA1-40241 detects Caveolin-1 from rat samples. MA1-40241 recognizes caveolin-1 alpha as well as caveolin-1 beta, which are present in many tissues, like aorta, heart, muscle, lung, adipose white, brown and epidydimal fat. MA1-40241 can be used to immuno-isolate caveolae. MA1-40241 has been successfully used in immunofluorescence, immunoprecipitation and Western blot applications. The MA1-40241 immunogen is rat caveolin. Positive control: Adipocytes (3T3-L1 adipocytes); Negative control: Cytoplasmic extracts of adipocytes.

Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation. It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Caveolin 1
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 7C8
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA and 0.02% sodium azide
Gene CAV1
Gene Accession No. P41350
Gene Alias BSCL3; CAV; CAV1; Cav-1; caveolae; caveolin 1; caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa; caveolin 1a; caveolin 1b; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; caveolin-1; caveolin-1a; caveolin-1b; cell growth-inhibiting protein 32; CGL3; HGNC:1527; LCCNS; MSTP085; OTTHUMP00000196475; PPH3; Unknown (protein for IMAGE:7985573); variant a; variant b; vesicular integral-membrane protein VIP21; VIP21; wu:fc07c04
Gene Symbols CAV1
Host Species Mouse
Immunogen Rat caveolin-1.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25404
Target Species Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2b
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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