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Invitrogen™ Caveolin 1 Monoclonal Antibody (A3E6)
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Catalog No. FEMA550559
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100 μL
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FEMA550559 100 μL
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Catalog No. FEMA550559 Supplier Invitrogen™ Supplier No. MA550559
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Description

Mouse Monoclonal Antibody

Positive control: SiHa cell lysates, human liver tissue, human lung tissue, human lung carcinoma tissue. Predicted band size: 20 kDa Subcellular Location: Cell membrane, golgi apparatus membrane, trans-golgi network, caveola, membrane raft.

Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation. It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Caveolin 1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone A3E6
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene CAV1
Gene Accession No. Q03135
Gene Alias BSCL3; CAV; CAV1; Cav-1; caveolae; caveolin 1; caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa; caveolin 1a; caveolin 1b; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; caveolin-1; caveolin-1a; caveolin-1b; cell growth-inhibiting protein 32; CGL3; HGNC:1527; LCCNS; MSTP085; OTTHUMP00000196475; PPH3; Unknown (protein for IMAGE:7985573); variant a; variant b; vesicular integral-membrane protein VIP21; VIP21; wu:fc07c04
Gene Symbols CAV1
Host Species Mouse
Immunogen Recombinant protein within human Caveolin 1 aa 1-150.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 857
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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