Caveolin-1 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 6C2B2, Proteintech

Catalog No.	Quantity
50-173-6504	150 μL

Catalog No. 50-173-6504 Supplier Proteintech Group Inc Supplier No. 660671IG150UL

Description

Mouse Monoclonal Antibody

Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation. It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.

Specifications

• Antigen: Caveolin-1
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 6C2B2
• Concentration: 0.74 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: CAV1
• Gene Accession No.: P41350, P49817, Q03135, Q6RVA9
• Gene Symbols: CAV1
• Host Species: Mouse
• Immunogen: Caveolin-1 Fusion Protein Ag8049
• Purification Method: Protein G
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 12389, 25404, 404693, 857
• Target Species: Human, Mouse, Pig, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1