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Caveolin-2 Goat anti-Human, Mouse, Rat, Alexa Fluor 488, Clone: , R&D Systems™

Catalog No. IC5788G
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100 Tests
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IC5788G 100 Tests
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Catalog No. IC5788G Supplier R&D Systems Supplier No. IC5788G
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Description

Goat Polyclonal Antibody

Caveolin-2 is a cell membrane-associated member of the caveolin family of proteins. Although its predicted MW is 17kDa, it runs anomalously at 21-22kDa on SDS-PAGE. Caveolin-2 is not ubiquitous, but it is found in divergent cell types such as smooth muscle, endothelial, and skeletal muscle cells, plus fibroblasts and adipocytes. When expressed alone, Caveolin-2 forms monomers and homodimers; when expressed with Caveolin-1, it exists as part of a 150kDa, Caveolin-1 associated oligomeric complex. Human Caveolin-2 is 162 amino acids (aa) in length. It contains a central membrane-embedded sequence (aa 87-107) flanked by two cytoplasmic domains (aa 1-86 and 108-162). Caveolin-2 has been found phosphorylated at tyrosines 19 and 27, and at serines 20, 23 and 36.

Specifications

Antigen Caveolin-2
Applications Immunocytochemistry
Classification Polyclonal
Conjugate Alexa Fluor 488
Dilution Immunocytochemistry 1:10 dilution
Formulation Supplied in a saline solution containing BSA and Sodium Azide. with Sodium Azide
Gene Accession No. P51636
Gene Alias CAV, CAV2, caveolae protein, 20-kD, caveolin 2, caveolin 2 isoform a and b, caveolin-2, Caveolin2, MGC12294
Gene Symbols CAV2
Host Species Goat
Immunogen E. coli-derived recombinant human Caveolin-2, Met1-Lys86, Accession # P51636
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 858
Test Specificity Caveolin-2 antibodies are ideal for immunocytochemistry colocalization studies in caveolae. The unconjugated antibody detects endogenous human, mouse, and rat Caveolin-2 in Western blots.
Target Species Human, Mouse, Rat
Content And Storage Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Isotype IgG
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