Invitrogen™ Caveolin 3 Polyclonal Antibody

Catalog No.	Quantity
PIPA519116	100 μg

Catalog No. PIPA519116 Supplier Invitrogen™ Supplier No. PA519116

Description

Goat Polyclonal Antibody

This antibody is predicted to react with bovine, canine and porcine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.

Caveolin-3 (CAV3) acts as a scaffolding protein within the caveolar membrane. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-3 may also regulate voltage-gated potassium channels. It also plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. Caveolin-3 also mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae. Mutations in the gene can result in HyperCKmia, rippling muscle disease 2, cardiomyopathy, long QT syndrome 9, sudden infant death syndrome, and myopathy.

Specifications

• Antigen: Caveolin 3
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene: Cav3
• Gene Accession No.: P51637, P51638, P56539
• Gene Alias: AI385751; CAV; Cav3; Cav-3; caveolin 3; caveolin-3; LGMD1C; LQT9; M-cav; M-caveolin; MGC126100; MGC126101; MGC126129; structural protein; VIP21; VIP-21
• Gene Symbols: Cav3
• Host Species: Goat
• Immunogen: Synthetic peptide sequence (EHTDLEAQIVKDIH) corresponding to the N-terminus amino acids of CAV3 (aa 5-18).
• Purification Method: Ammonium sulfate precipitation
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 12391, 29161, 859
• Target Species: Human, Mouse, Rat, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG