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Invitrogen™ Caveolin 3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA585274

Catalog No. PIPA585274


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Description

Description

Keep as concentrated solution. Predicted reactivity: Dog (100%), Rhesus Monkey (100%), Bovine (100%). Positive Control: Rat muscle, mouse muscle. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Caveolin-3 (CAV3) acts as a scaffolding protein within the caveolar membrane. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-3 may also regulate voltage-gated potassium channels. It also plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. Caveolin-3 also mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae. Mutations in the gene can result in HyperCKmia, rippling muscle disease 2, cardiomyopathy, long QT syndrome 9, sudden infant death syndrome, and myopathy.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Caveolin 3
Polyclonal
Unconjugated
Cav3
AI385751; CAV; Cav3; Cav-3; caveolin 3; caveolin-3; LGMD1C; LQT9; M-cav; M-caveolin; MGC126100; MGC126101; MGC126129; structural protein; VIP21; VIP-21
Rabbit
Antigen affinity chromatography
RUO
12391, 29161, 859
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
P51637, P51638, P56539
Cav3
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Caveolin 3.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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