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Caveolin-3 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985529
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50-198-5529 100 μL
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Catalog No. 50-198-5529 Supplier Bioss Supplier No. BS3610R
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Description

Rabbit Polyclonal Antibody

Caveolin-3 (CAV3) acts as a scaffolding protein within the caveolar membrane. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-3 may also regulate voltage-gated potassium channels. It also plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. Caveolin-3 also mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae. Mutations in the gene can result in HyperCKmia, rippling muscle disease 2, cardiomyopathy, long QT syndrome 9, sudden infant death syndrome, and myopathy.

Specifications

Antigen Caveolin-3
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Cav3
Gene Accession No. P56539
Gene Alias AI385751; CAV; Cav3; Cav-3; caveolin 3; Caveolin-3; LGMD1C; LQT9; M-cav; M-caveolin; MGC126100; MGC126101; MGC126129; VIP21; VIP-21
Gene Symbols Cav3
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from mouse Caveolin-3.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 859
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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