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Invitrogen™ Caveolin 3 Recombinant Rabbit Monoclonal Antibody (4G5W2)
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Catalog No. PIMA542865
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100 μL
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PIMA542865 100 μL
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Catalog No. PIMA542865 Supplier Invitrogen™ Supplier No. MA542865
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Description

Rabbit Recombinant Monoclonal Antibody

Positive test controls include: Mouse lung, Mouse heart, Rat heart. The target is usually found in the following locations: Cell membrane, Golgi apparatus membrane, Membrane, Peripheral membrane protein, caveola. Immunogen sequence: MMAEEHTDLE AQIVKDIHCK EIDLVNRDPK NINEDIVKVD FEDVIAEPVG TYSFDGVWKV SYTTFTVSKY WCYRLLSTLL GVPLALLWGF LFACISFCHI WAVVPCIKSY LIEIQCISHI YSLCIRTFCN PLFAALGQVC SSIKVVLRKE V.

Caveolin-3 (CAV3) acts as a scaffolding protein within the caveolar membrane. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-3 may also regulate voltage-gated potassium channels. It also plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. Caveolin-3 also mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae. Mutations in the gene can result in HyperCKmia, rippling muscle disease 2, cardiomyopathy, long QT syndrome 9, sudden infant death syndrome, and myopathy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Caveolin 3
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 4G5W2
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Cav3
Gene Accession No. P51637, P51638, P56539
Gene Alias AI385751; CAV; Cav3; Cav-3; caveolin 3; caveolin-3; LGMD1C; LQT9; M-cav; M-caveolin; MGC126100; MGC126101; MGC126129; structural protein; VIP21; VIP-21
Gene Symbols Cav3
Host Species Rabbit
Immunogen Recombinant protein (or fragment)).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12391, 29161, 859
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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