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Tocris Bioscience™ CB 5083

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Quantity:
5 mg
25 mg
Description
CB 5083 is a potent p97 inhibitor, inhibiting the D2 ATPase domain (IC50 = 11 nM). CB 5083 shows broad antitumor activity and inhibits tumor growth in vivo. CB 5083 is cytotoxic to A549 cancer cells (IC50 = 680 nM), increases CHOP and GRP78 protein levels and results in the loss of aggresomes.
Specifications
Specifications
Chemical Name or Material | 1-[7,8-Dihydro-4-[(phenylmethyl)amino]-5 H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1 H-indole-4-carboxamide |
CAS | 1542705-92-9 |
Quantity | 5 mg |
Target | p97 ATPase Inhibitors |
Molecular Formula | C24H23N5O2 |
Purity | 0.98 |
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