Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Tocris Bioscience™ CB 5083
GREENER_CHOICE

Catalog No. 73795
Click to view available options
Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Potent p97 ATPase inhibitor

CB 5083 is a potent p97 inhibitor, inhibiting the D2 ATPase domain (IC50 = 11 nM). CB 5083 shows broad antitumor activity and inhibits tumor growth in vivo. CB 5083 is cytotoxic to A549 cancer cells (IC50 = 680 nM), increases CHOP and GRP78 protein levels and results in the loss of aggresomes.

Specifications

Chemical Name or Material 1-[7,8-Dihydro-4-[(phenylmethyl)amino]-5 H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1 H-indole-4-carboxamide
CAS 1542705-92-9
Quantity 5 mg
Target p97 ATPase Inhibitors
Molecular Formula C24H23N5O2
Purity 0.98
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.