CBF-beta (isoform 1) Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-156-5442	Bethyl Laboratories, Inc A303549AT	20 μL

Description

The recommended shelf life for this product is 1 year from date of receipt.

CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters.

Specifications

• Antigen: CBF-beta (isoform 1)
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: CBF-beta, PEA2-beta, PEBP2B, PEBP2-beta, polyomavirus enhancer binding protein 2, beta subunit, polyomavirus enhancer-binding protein 2 beta subunit, SL3/AKV core-binding factor beta subunit, SL3-3 enhancer factor 1 beta subunit, SL3-3 enhancer factor 1 subunit beta
• Immunogen: Between 166 and 187
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: CBFB

• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q08024, Q13951
• Gene ID (Entrez): 12400, 865
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody