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CBLN1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981690
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50-198-1690 100 μL
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Catalog No. 50-198-1690 Supplier Bioss Supplier No. BS11814R
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Rabbit Polyclonal Antibody

Precerebellin is the precursor of the brain-specific hexadecapeptide cerebellin, a protein with substantial similarity to the globular region of the B chain of complement component C1q. Cerebellin exerts neuromodulatory functions by directly stimulating norepinephrine release via the adenylate cyclase/pka- dependent signaling pathway; and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release. The active form of precerebellin is highly enriched in postsynaptic structures of cerebellar Purkinje cells in cartwheel neurons of the dorsal cochlear nucleus. Because precerebellin belongs to the C1q/tumor necrosis factor superfamily of secreted proteins and has similarity to adiponectin and CTRP3, it has been suggested that precerebellin posseses functions other than those already stated.

Specifications

Antigen CBLN1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CBLN1
Gene Accession No. P23435
Gene Alias [des-Ser1]CER; [des-Ser1]-cerebellin; AI323299; Brain protein D3; Cbln1; CER; Cerebellin; cerebellin 1 precursor; cerebellin 1 precursor protein; Cerebellin-1; des-Ser(1)-cerebellin; des-Ser1-cerebellin; Precerebellin
Gene Symbols CBLN1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human CBLN1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 869
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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