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CBLN4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

$518.60

Specifications

Antigen CBLN4
Concentration 0.19 mg/mL
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-173-2961
SDP
Encompass_Preferred
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Proteintech Group Inc
205591AP150UL
150 μL
Each of 1 for $518.60
Only null left
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Description

Description

The antibody has no cross reaction to CBLN1, 2, or 3.

Cerebellin (CER), which was originally isolated from rat cerebellum, is a hexadecapeptide derived from a larger precursor called Cerebellin 1, also designated precerebellin 1 or Cbln1. Four propeptides, Cerebellin 1, Cerebellin 2 (Cbln2), Cerebellin 3 (Cbln3) and Cerebellin 4 (Cbln4), comprise the precerebellin subfamily within the C1q protein family. Cerebellin family members act as transneuronal regulators of synapse development and synaptic plasticity in various brain regions. Cerebellin and its metabolite, des-Ser(1)Cer, are also expressed in several extra-cerebellar tissues, including adrenal gland. Cerebellin 1, 2 and 3 assemble into homomeric and heteromeric complexes, thereby influencing each other′s degradation and secretion. Cerebellin 3 is not able to form homomeric complexes, and can only be secreted upon forming a heteromeric complex with Cerebellin 1. Decreased concentrations of Cerebellin have been found in the brain of patients with olivopontocerebellar atrophy (OPCA) and Shy-Drager syndrome, suggesting a role for Cerebellin in the pathology of these diseases.
Specifications

Specifications

CBLN4
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Rabbit
Human, Mouse, Rat
Q8BME9, Q9NTU7
140689, 228942, 499947
Peptide
Primary
-20°C
CBLN4
0.19 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
CBLN4, CBLNL1, Cerebellin 4, cerebellin 4 precursor, Cerebellin like glycoprotein 1
Cbln4
IgG
Antigen Affinity Chromatography
Antibody
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SDS
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Documents

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