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CBP/EIF4E Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 111491AP150UL

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Catalog No. 50-172-6918


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Description

Description

This is a rabbit polyclonal antibody raised against the full-length human EIF4E protein. This protein can form a dimer (∽50 kDa).

eIF4E is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A, that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G.
Specifications

Specifications

CBP/EIF4E
Polyclonal
Unconjugated
EIF4E
CBP, eIF 4E, eIF 4F 25 kDa subunit, EIF4E, EIF4E1, EIF4EL1, EIF4F, mRNA cap binding protein
Rabbit
Antigen Affinity Chromatography
RUO
117045, 13684, 1977
-20°C
Liquid
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.17 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P06730, P63073, P63074
Eif4e
CBP,EIF4E Fusion Protein Ag1626
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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