Invitrogen™ CBS Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120263

Catalog No. PIPA5120263

Description

Positive test controls include: HepG2, 293T, HeLa, MCF7, Mouse liver, Rat liver, Rat kidney. The target is usually found in the following locations: Cytoplasm, Nucleus. Immunogen sequence: MPSETPQAEV GPTGCPHRSG PHSAKGSLEK GSPEDKEAKE PLWIRPDAPS RCTWQLGRPA SESPHHHTAP AKSPKILPDI LKKIGDTPMV RINKIGKKFG LKCELLAKCE FFNAGGSVKD RISLRMIEDA ERDGTLKPGD TIIEPTSGNT GIGLALAAAV RGYRCIIVMP EKMSSEKVDV LRALGAEIVR TPTNARFDSP ESHVGVAWRL KNEIPNSHIL DQYRNASNPL AHYDTTADEI LQQCDGKLDM LVASVGTGGT ITGIARKLKE KCPGCRIIGV DPEGSILAEP EELNQTEQTT YEVEGIGYDF IPTVLDRTVV DKWFKSNDEE AFTFARMLIA QEGLLCGGSA GSTVAVAVKA AQELQEGQRC VVILPDSVRN YMTK.

Only known pyridoxal phosphate-dependent enzyme that contains heme. Important regulator of hydrogen sulfide, especially in the brain, utilizing cysteine instead of serine to catalyze the formation of hydrogen sulfide. Hydrogen sulfide is a gastratransmitter with signaling and cytoprotective effects such as acting as a neuromodulator in the brain to protect neurons against hypoxic injury.

Specifications

• Antigen: CBS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CBS
• Gene Alias: AI047524; AI303044; Beta-thionase; Cbs; CBSL; cystathionine beta synthase; cystathionine beta-synthase; cystathionine beta-synthase; LOW QUALITY PROTEIN: cystathionine beta-synthase; Cystathionine beta-synthase-like protein; cystathionine-beta-synthase; hemoprotein H-450; HIP4; LOC100057612; methylcysteine synthase; serine sulfhydrase
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12411, 24250, 875
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.93 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: P32232, P35520, Q91WT9
• Gene Symbols: CBS
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-384 of human CBS (NP_0000621).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG