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Invitrogen™ CBWD2 Polyclonal Antibody
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Catalog No. PA540114
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100 μL
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PA540114 100 μL
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Catalog No. PA540114 Supplier Invitrogen™ Supplier No. PA540114
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: THP-1 cells. Predicted reactivity: Human (99%), Dog (88%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The CBWD2 gene, a member of the CobW domain-containing (CBWD) gene family, encodes a protein involved in vitamin B12 synthesis. This gene is part of a conserved pathway crucial for cobalamin biosynthesis, typically in microorganisms. In dinoflagellates, the CBWD gene family, including CBWD2, has been identified to play a role in the synthesis and regulation of vitamin B12, essential for various metabolic processes. The CobW domain is implicated in interactions with cobalt, a vital component of the vitamin B12 molecule, suggesting a regulatory or structural role in cobalamin assembly. Research on the CBWD2 gene and its protein products can provide insights into the complex mechanisms of vitamin B12 biosynthesis and its evolutionary significance in eukaryotic organisms, possibly opening avenues for biotechnological applications in vitamin B12 production.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CBWD2
Applications Western Blot
Classification Polyclonal
Concentration 0.97 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% Thimerosal; pH 7
Gene CBWD2
Gene Accession No. Q8IUF1
Gene Alias CBWD2; Cobalamin synthase W domain-containing protein 2; cobalamin synthetase W domain-containing protein 2; COBW domain containing 2; COBW domain-containing protein 2
Gene Symbols CBWD2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human CBWD2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 150472
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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