Invitrogen™ CBWD6 Polyclonal Antibody

Catalog No.	Quantity
PA549247	400 μL

Catalog No. PA549247 Supplier Invitrogen™ Supplier No. PA549247

Description

Rabbit Polyclonal Antibody

CBWD6 Polyclonal Antibody for Western Blot

Zinc chaperone that directly transfers zinc cofactor to target metalloproteins, thereby activating them (By similarity). Catalyzes zinc insertion into the active site of methionine aminopeptidase METAP1, which function to cleave the initiator methionine from polypeptides during or after protein translation. Mechanistically, the N-terminal psi-PxLVp motif binds to the C6H2-type zinc finger of inactive form of METAP1 (By similarity). After formation of the docked complex, zinc is transferred from the CXCC motif in the GTPase domain of ZNG1F to the zinc binding site in the peptidase domain of METAP1 in a process requiring GTP hydrolysis (By similarity). GTP/GDP exchange is required for release of active METAP1 (By similarity).

Specifications

• Antigen: CBWD6
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene: CBWD6
• Gene Accession No.: Q4V339
• Gene Alias: CBWD6; CBWD7; Cobalamin synthase W domain-containing protein 6; cobalamin synthetase W domain-containing protein 6; COBW domain containing 6; COBW domain-containing protein 6
• Gene Symbols: CBWD6
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide between 193-221 amino acids from the Central region of human CBWD6.
• Purification Method: Antigen affinity chromatography, Protein A
• Quantity: 400 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 644019
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG