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Invitrogen™ CBX4 Polyclonal Antibody
Rabbit Polyclonal Antibody
$589.50
Specifications
| Antigen | CBX4 |
|---|---|
| Concentration | 0.20 mg/mL |
| Content And Storage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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PIPA5110742
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Invitrogen™
PA5110742 |
100 μL |
Each for $589.50
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PIPA5110770
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Invitrogen™
PA5110770 |
100 μL |
Each for $589.50
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Description
Immunogen sequence: SPKYNTWEPE ENILDPRLLI AFQNRERQEQ LMGYRKRGPK PKPLVVQVPT FARRSNVLTG LQDSSTDNRA KLDSGAEEK.
Polycomb group (PcG) proteins are chromatin-associated proteins which are important for embryonic and adult stem cell self-renewal and maintenance. At least two distinct human PcG complexes have been identified. Polycomb repressive complex I (PRC1) contains CBX4/Pc2, HPH1 and RING domain-containing proteins (RING1, RING2 and BMI1). CBX4 (Chromobox protein homolog 4 or PC2), which functions as a transcriptional suppressor, is a candidate of KyoT2-binding proteins. It is a E3 SUMO-protein ligase which facilitates SUMO1 conjugation. Depletion of CBX4 results in decreased cellular resistance to ionizing radiation. CBX4 is directly involved in the cellular response to DNA damage.Specifications
| CBX4 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human | |
| CBX4 | |
| Cbx4; chromobox 4; chromobox homolog 4; chromobox homolog 4 (Pc class homolog, Drosophila); chromobox protein homolog 4; chromobox-like protein 4; E3 SUMO-protein ligase CBX4; E3 SUMO-protein transferase CBX4; hPc2; MPc2; NBP16; NS5ATP1-binding protein 16; Pc class 2 homolog; PC2; Polycomb 2 homolog | |
| CBX4 | |
| Primary | |
| Antigen affinity chromatography |
| 0.20 mg/mL | |
| Immunohistochemistry (Paraffin) | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| O00257 | |
| 8535 | |
| Recombinant Protein corresonding to Human CBX4. Recombinant protein control fragment (Product #RP-89355). | |
| Antibody |
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