CBX5 Mouse anti-Human, Mouse, Clone:1B10B2, Abnova™

Mouse monoclonal antibody raised against recombinant human CBX5.

Supplier:  Abnova Corporation MAB17166

Catalog No. 89-333-487

Description

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]

Specifications

• Antigen: CBX5
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000)
  Western Blot (1:500-1:2000)
  Immunohistochemistry (1:200-1:1000)
  Immunocytochemistry (1:200-1:1000)
  Flow Cytometry
  The optimal working dilution should be determined by the end user.
• Gene: CBX5
• Host Species: Mouse
• Quantity: 100 μg
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Clone: 1B10B2
• Description: chromobox homolog 5 (HP1 alpha homolog, Drosophila)
• Formulation: In PBS (0.05% sodium azide)
• Gene Alias: HP1, HP1A
• Immunogen: Recombinant protein corresponding to amino acid 1-191 of human CBX5 from E. coli.
• Gene ID (Entrez): 23468
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid