Invitrogen™ CBX6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA541549

Catalog No. PIPA541549

Description

Peptide sequence: FAAESIIKRR IRKGRIEYLV KWKGWAIKYS TWEPEENILD SRLIAAFEQK Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. CBX6 (chromobox protein homolog 6) is a 412 amino acid protein that is a component of the chromatin-associated PcG complex. Through interaction with PcG, CBX6 modifies chromatin and maintains the transcriptionally repressive state of genes. Members of the chromobox domain protein family are characterized by the presence of a 37 amino acid chromobox (CHRromatin Organization MOdifier) domain. This domain plays a mechanistic role in targeting chromodomain proteins to specific regions of the nucleus.

Specifications

• Antigen: CBX6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CBX6
• Gene Alias: CBX6; chromobox 6; chromobox homolog 6; chromobox protein homolog 6; chromobox-like protein 6
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 23466
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: O95503
• Gene Symbols: CBX6
• Immunogen: Synthetic peptide directed towards the N-terminal of human CBX6 (aa 11-60).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG