Invitrogen™ CBX7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA561801

Catalog No. PIPA561801

Description

Immunogen sequence: ADADLAEGPP PWTPALPSSE VTVTDITANS ITVTFREAQA AEGFFRDRSG KF Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 88%.

The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.

Specifications

• Antigen: CBX7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CBX7
• Gene Alias: 1600014J01Rik; AI851678; Cbx7; chromobox 7; chromobox homolog 7; chromobox protein homolog 7; chromobox-like protein 7; D15Ertd417e
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23492
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O95931
• Gene Symbols: CBX7
• Immunogen: Recombinant protein corresponding to Human CBX7. Recombinant protein control fragment (Product #RP-103031).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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