Invitrogen™ CBX8 Monoclonal Antibody (9C3D4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA517039

Catalog No. PIMA517039

Description

MA5-17039 targets CBX8 in FACS, indirect ELISA, and WB applications and shows reactivity with Human samples. The MA5-17039 immunogen is purified recombinant fragment of human CBX8 (amino acids: 17-222) expressed in E. Coli. MA5-17039 detects CBX8 which has a predicted molecular weight of approximately 43.4kDa.

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Specifications

• Antigen: CBX8
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: Q9HC52
• Gene Symbols: CBX8
• Immunogen: Purified recombinant fragment of human CBX8 (amino acids: 17-222) expressed in E. Coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Western Blot
• Clone: 9C3D4
• Conjugate: Unconjugated
• Gene: CBX8
• Gene Alias: CBX8; chromobox 8; chromobox homolog 8; chromobox homolog 8 (Pc class homolog, Drosophila); chromobox protein homolog 8; HPC3; mPc3; Pc class 3 homolog; Pc3; polycomb 3; polycomb 3 homolog; RC1; rectachrome 1
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 57332
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid