CBX8 Mouse anti-Human, Clone: OTI6D9, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF800491

Catalog No. 50-166-5134

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Chromobox homolog 8 (CBX8 or Pc3) is a member of Drosophila Polycomb group gene family. The polycomb group (PcG) genes are essential for maintece of appropriate expression patterns of developmental master regulators and thus are essential for proper development. Changes in expression of PcG proteins have been associated with cancer. CBX8 is involved in maintaining the transcriptionally repressive state of genes. It modifies chromatin, rendering it heritably changed in its expressibility. Structurally, CBX4 contains 1 chromo domain, which is 40 to 50 amino acids long.

Specifications

• Antigen: CBX8
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: CBX8
• Gene Alias: PC3, RC1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57332
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI6D9
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q9HC52
• Gene Symbols: CBX8
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-260 of human CBX8 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b