Invitrogen™ CBX8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103359

Catalog No. PIPA5103359

Description

Antibody detects endogenous levels of total CBX8.

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Specifications

• Antigen: CBX8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CBX8
• Gene Alias: CBX8; chromobox 8; chromobox homolog 8; chromobox homolog 8 (Pc class homolog, Drosophila); chromobox protein homolog 8; HPC3; mPc3; Pc class 3 homolog; Pc3; polycomb 3; polycomb 3 homolog; RC1; rectachrome 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 303731, 30951, 57332
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9HC52, Q9QXV1
• Gene Symbols: CBX8
• Immunogen: A synthesized peptide derived from human CBX8(Accession Q9HC52), corresponding to amino acid residues R158-P208.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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