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Tocris Bioscience™ CC 401 dihydrochloride
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Catalog No. 625850
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Catalog No. Quantity
62-585-0 50 mg
62-581-0 10 mg
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Catalog No. 62-585-0 Supplier Tocris Bioscience™ Supplier No. 6258/50
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Description

High affinity JNK inhibitor; also inhibits HCMV replication

High affinity JNK inhibitor (Ki values are 25-50 nM). Inhibits JNK via competitive binding of the ATP-binding site of active, phosphorylated JNK. Exhibits > 40-fold selectivity for JNK over p38, ERK, IKK2, protein kinase C, Lck and ZAP70. Hepatoprotective. Also inhibits HCMV replication.

Chemical Identifiers

CAS 2250025-96-6

Specifications

Quantity 50 mg
Solubility Soluble to 100mM in water and to 100mM in DMSO
Formula Weight 461.39
Physical Form Solid
Purity >98%
Chemical Name or Material 3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole dihydrochloride

Safety and Handling

Recommended Storage Store at -20°C
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