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CC2D1A Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501572055
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50-157-2055 100 μL
50-157-2056 10 μL
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Catalog No. 50-157-2055 Supplier Bethyl Laboratories, Inc Supplier No. IHC00414
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Orangutan, Gorilla and Chimpanzee

Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses (By similarity). Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis.

Specifications

Antigen CC2D1A
Applications Immunofluorescence, Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene CC2D1A
Gene Accession No. Q6P1N0
Gene Alias Akt kinase-interacting protein 1, five prime repressor element under dual repression-binding protein 1, five repressor element under dual repression-binding protein 1, FLJ20241, FRE under dual repression-binding protein 1, FREUD-1, Freud-1/Aki1, mental retardation, nonsyndromic, autosomal recessive, 3, MRT3, putative NF-kappa-B-activating protein 023N, putative NFkB activating protein
Gene Symbols CC2D1A
Host Species Rabbit
Immunogen Between 1 and 50
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54862
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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