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Invitrogen™ CCBE1 Polyclonal Antibody
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Catalog No. PIPA543842
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100 μL
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PIPA543842 100 μL
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Catalog No. PIPA543842 Supplier Invitrogen™ Supplier No. PA543842
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Description

Rabbit Polyclonal Antibody

Peptide sequence: PMGPSPDLSH IKQGRRGPVG PPGAPGRDGS KGERGAPGPR GSPGPPGSFD Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

The gene encoding CCBE1 (Collagen and calcium-binding EGF domain-containing protein 1) is located on chromosome 18 in a region that is frequently found to be deleted in breast and prostate cancers. CCBE1 is a 406 amino acid secreted protein that contains two collagen-like domains and one calcium-binding epidermal growth factor (EGF-like) domain. In general, EGF-like domains include six cysteine residues that are usually involved in disulfide bonds. Calcium-binding EGF-like domains are subject to amino acid substitutions that disrupt their structure or calcium affinity, therefore altering protein function. Downregulation of the gene encoding CCBE1 is observed with high frequency in breast cancer, suggesting that loss of CCBE1 results in changes in cell adhesion and mobility due to its characterization as an extracellular protein. There are three named isoforms of CCBE1 which are produced as a result of alternative splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCBE1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene CCBE1
Gene Accession No. Q6UXH8
Gene Alias 4933426F18Rik; 9430093N24Rik; CCBE1; collagen and calcium binding EGF domains 1; collagen and calcium-binding EGF domain-containing protein 1; FLJ30681; fof; full of fluid protein; Full of fluid protein homolog; HKLLS1; KIAA1983; MGC50861; mKIAA1983; RGD1307670; UNQ1921/PRO4395
Gene Symbols CCBE1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human CCBE1.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 147372
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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