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Invitrogen™ CCDC105 Polyclonal Antibody
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Catalog No. PIPA563588
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100 μL
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PIPA563588 100 μL
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Catalog No. PIPA563588 Supplier Invitrogen™ Supplier No. PA563588
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RDTLNFCFKE RLQAVDLMNQ PLDKVLEQAR RHSWVNLSRA PTPRTQGQKT PPPDPVGTYN PACALALNEA KR Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 79%.

CCDC105 (Coiled-Coil Domain-Containing 105) is a gene that encodes a protein involved in various cellular processes, primarily associated with the structure and function of centrioles and cilia. The CCDC105 protein contains coiled-coil domains that facilitate protein-protein interactions, crucial for the assembly and stabilization of microtubule structures within cells. Studies indicate that CCDC105 plays a key role in ciliogenesis, the process by which cells form cilia, which are essential for cell motility, fluid movement, and signal transduction. Dysregulation or mutations in CCDC105 have been implicated in ciliopathies, a group of disorders arising from defective cilia, leading to symptoms such as respiratory issues, kidney disease, and developmental abnormalities. Research continues to explore the specific molecular mechanisms by which CCDC105 influences ciliary dynamics and its broader implications in human health and disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCDC105
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CCDC105
Gene Accession No. Q8IYK2
Gene Alias CCDC105; coiled-coil domain containing 105; coiled-coil domain-containing protein 105
Gene Symbols CCDC105
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CCDC105. Recombinant protein control fragment (Product #RP-99135).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 126402
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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