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Invitrogen™ CCDC106 Polyclonal Antibody
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Catalog No. PIPA559790
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100 μL
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PIPA559790 100 μL
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Catalog No. PIPA559790 Supplier Invitrogen™ Supplier No. PA559790
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MNDRSSRRRT MKDDETFEIS IPFDEAPHLD PQIFYSLSPS RRNFEEPPEA ASSALALMNS VKTQLHMALE RNSWLQKRIE DLEEERDFLR CQ Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 90%.

The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCDC106
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CCDC106
Gene Accession No. Q9BWC9
Gene Alias BC018462; CCDC106; coiled-coil domain containing 106; coiled-coil domain-containing protein 106; HSU79303; MNCb-2071; protein predicted by clone 23882; RGD1566222; ZNF581
Gene Symbols CCDC106
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CCDC106. Recombinant protein control fragment (Product #RP-99160).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29903
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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