Invitrogen™ CCDC106 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA560281

Catalog No. PIPA560281

Description

Immunogen sequence: KLKSMSRAFE HHRVDRNTVA LTTPIAELLI VAPEKLAEVG EFDPSKERLL EYSRRCFLAL DDETLKKVQA LKKSKLLLPI TYRFK Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.

Specifications

• Antigen: CCDC106
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCDC106
• Gene Alias: BC018462; CCDC106; coiled-coil domain containing 106; coiled-coil domain-containing protein 106; HSU79303; MNCb-2071; protein predicted by clone 23882; RGD1566222; ZNF581
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29903
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BWC9
• Gene Symbols: CCDC106
• Immunogen: Recombinant protein corresponding to Human CCDC106. Recombinant protein control fragment (Product #RP-99161).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG