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Invitrogen™ CCDC109B Polyclonal Antibody
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Catalog No. PIPA561817
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100 μL
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Catalog No. Quantity
PIPA561817 100 μL
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Catalog No. PIPA561817 Supplier Invitrogen™ Supplier No. PA561817
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SNEHTAEMEH MKSLVHRLFT ILHLEESQKK REHHLLEKID HLKEQLQPLE QVKAGIEAHS E Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 74%.

Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCDC109B
Applications Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene MCUB
Gene Accession No. Q9NWR8
Gene Alias calcium uniporter regulatory subunit MCUb, mitochondrial; CCDC109B; coiled-coil domain containing 109B; coiled-coil domain-containing protein 109B; MCUB; mitochondrial calcium uniporter dominant negative beta subunit; mitochondrial calcium uniporter regulatory subunit MCUb
Gene Symbols MCUB
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CCDC109B. Recombinant protein control fragment (Product #RP-101087).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55013
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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