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Invitrogen™ CCDC123 Polyclonal Antibody
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Catalog No. PIPA558767
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100 μL
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PIPA558767 100 μL
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Catalog No. PIPA558767 Supplier Invitrogen™ Supplier No. PA558767
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QVLKDKQEVL DQALQQNREM EGELEVIWES TFRENRRIRE LLQDTLTRTG VQDNPRALVA PSLNGVSQAD LLDGCDVCSY D Highest antigen sequence identity to the following orthologs: Mouse - 52%, Rat - 51%.

CCDC123 (as known as CEP123), also named as CEP89, is a new player in the process of primary ciliogenesis and it also plays a role in mitochondrial metabolism where it may modulate complex IV activity. It has been shown that CEP123 is localized to the distal appendages of the mother centriole and the localization of CEP123 is cell cycle-dependent with its levels decreasing during mitosis. CEP123 depletion can cause defects in ciliary vesicle formation and prevent the formation of a ciliary vesicle at the distal end of the mother centriole. It is possible that CEP123 is involved in regulating the recruitment of membranes to the centrosome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCDC123
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.7 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CEP89
Gene Accession No. Q96ST8
Gene Alias 2610507L03Rik; CCDC123; centrosomal protein 123; centrosomal protein 89; centrosomal protein 89kDa; centrosomal protein of 89 kDa; Cep123; Cep89; coiled-coil domain containing 123; Coiled-coil domain-containing protein 123; coiled-coil domain-containing protein 123, mitochondrial
Gene Symbols CEP89
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CCDC123. Recombinant protein control fragment (Product #RP-102870).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84902
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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