Invitrogen™ CCDC123 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA558767

Catalog No. PIPA558767

Description

Immunogen sequence: QVLKDKQEVL DQALQQNREM EGELEVIWES TFRENRRIRE LLQDTLTRTG VQDNPRALVA PSLNGVSQAD LLDGCDVCSY D Highest antigen sequence identity to the following orthologs: Mouse - 52%, Rat - 51%.

CCDC123 (as known as CEP123), also named as CEP89, is a new player in the process of primary ciliogenesis and it also plays a role in mitochondrial metabolism where it may modulate complex IV activity. It has been shown that CEP123 is localized to the distal appendages of the mother centriole and the localization of CEP123 is cell cycle-dependent with its levels decreasing during mitosis. CEP123 depletion can cause defects in ciliary vesicle formation and prevent the formation of a ciliary vesicle at the distal end of the mother centriole. It is possible that CEP123 is involved in regulating the recruitment of membranes to the centrosome.

Specifications

• Antigen: CCDC123
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CEP89
• Gene Alias: 2610507L03Rik; CCDC123; centrosomal protein 123; centrosomal protein 89; centrosomal protein 89kDa; centrosomal protein of 89 kDa; Cep123; Cep89; coiled-coil domain containing 123; Coiled-coil domain-containing protein 123; coiled-coil domain-containing protein 123, mitochondrial
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84902
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.7 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96ST8
• Gene Symbols: CEP89
• Immunogen: Recombinant protein corresponding to Human CCDC123. Recombinant protein control fragment (Product #RP-102870).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG