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Invitrogen™ CCDC123 Polyclonal Antibody
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Catalog No. PIPA5114273
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PIPA5114273 100 μL
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Catalog No. PIPA5114273 Supplier Invitrogen™ Supplier No. PA5114273
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PNPSPERPRS ALAAAILATT LTGRTVAIPQ PRQRSRSESD VSSVEQDSFI For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Guinea Pig: 85%; Horse: 91%; Human: 100%; Mouse: 92%; Rat: 92%.

CCDC123 (as known as CEP123), also named as CEP89, is a new player in the process of primary ciliogenesis and it also plays a role in mitochondrial metabolism where it may modulate complex IV activity. It has been shown that CEP123 is localized to the distal appendages of the mother centriole and the localization of CEP123 is cell cycle-dependent with its levels decreasing during mitosis. CEP123 depletion can cause defects in ciliary vesicle formation and prevent the formation of a ciliary vesicle at the distal end of the mother centriole. It is possible that CEP123 is involved in regulating the recruitment of membranes to the centrosome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCDC123
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene CEP89
Gene Accession No. Q96ST8
Gene Alias 2610507L03Rik; CCDC123; centrosomal protein 123; centrosomal protein 89; centrosomal protein 89kDa; centrosomal protein of 89 kDa; Cep123; Cep89; coiled-coil domain containing 123; Coiled-coil domain-containing protein 123; coiled-coil domain-containing protein 123, mitochondrial
Gene Symbols CEP89
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal region of Human CEP89 (aa 41-90).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84902
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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