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Invitrogen™ CCDC127 Polyclonal Antibody
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Catalog No. PIPA5113214
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100 μg
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PIPA5113214 100 μg
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Catalog No. PIPA5113214 Supplier Invitrogen™ Supplier No. PA5113214
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Description

Rabbit Polyclonal Antibody

CCDC127 Polyclonal Antibody for Western Blot, ELISA

CCDC127 (Coiled-Coil Domain-Containing 127) is a gene that has been identified as a key regulator of lipid droplet (LD) homeostasis by enhancing the mitochondria-ER contact sites (MERCS). This gene encodes a protein with coiled-coil domains, which facilitate interactions with other proteins and cellular structures. CCDC127 plays a critical role in the formation and maintenance of LDs, which are essential organelles for storing neutral lipids and are involved in lipid metabolism and energy homeostasis. Knockdown and overexpression studies in HeLa cells have shown that CCDC127 positively regulates LD abundance, suggesting its importance in cellular lipid management. Additionally, it has been observed that CCDC127 impacts adipose differentiation, indicating its broader role in lipid biology and potential implications in metabolic diseases. The ability of CCDC127 to modulate MERCS highlights its significance in cellular lipid dynamics and organelle communication.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCDC127
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene CCDC127
Gene Accession No. Q3TC33, Q96BQ5
Gene Alias 0610011N22Rik; 5430420E17Rik; A430066A18; AI256405; AW050060; C130002N06; CCDC127; coiled-coil domain containing 127; coiled-coil domain-containing protein 127; RGD735106
Gene Symbols CCDC127
Host Species Rabbit
Immunogen Recombinant Human Coiled-coil domain-containing protein 127 protein (1-260AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 133957, 67433
Target Species Human, Mouse
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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