Invitrogen™ CCDC134 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA520780

Catalog No. PIPA520780

Description

A suggested positive control is rat brain tissue lysate. PA5-20780 can be used with blocking peptide PEP-0894.

The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. One such protein is CCDC134, a recently identified secretory protein that has been found to inhibit the transcriptional activity of the Elk1 protein. Overexpression CCDC134 also inhibited the phosphorylation of Erk and JNK/SAPK but not p38 MAPK, while specific siRNA against CCDC134 activated Elk1 transcriptional activity and the phosphorylation of Erk and JNK/SAPK, suggesting a potential inhibiting role of CCDC134 in MAPK-mediated Elk1 transcription. CCDC134 is widely expressing in normal adult tissues, tumors, and cell lines.

Specifications

• Antigen: CCDC134
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCDC134
• Gene Alias: 2310042L06Rik; AW208859; Ccdc134; coiled-coil domain containing 134; coiled-coil domain-containing protein 134; dJ821D11.3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 500909, 76457, 79879
• Content And Storage: 4°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q5M862, Q8C7V8, Q9H6E4
• Gene Symbols: CCDC134
• Immunogen: A 17 amino acid peptide near the amino terminus of human CCDC134.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG