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Invitrogen™ CCDC134 Recombinant Rabbit Monoclonal Antibody (026)
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Catalog No. PIMA529088
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100 μL
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Catalog No. Quantity
PIMA529088 100 μL
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Catalog No. PIMA529088 Supplier Invitrogen™ Supplier No. MA529088
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Description

Rabbit Recombinant Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Human CCDC134.

The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. One such protein is CCDC134, a recently identified secretory protein that has been found to inhibit the transcriptional activity of the Elk1 protein. Overexpression CCDC134 also inhibited the phosphorylation of Erk and JNK/SAPK but not p38 MAPK, while specific siRNA against CCDC134 activated Elk1 transcriptional activity and the phosphorylation of Erk and JNK/SAPK, suggesting a potential inhibiting role of CCDC134 in MAPK-mediated Elk1 transcription. CCDC134 is widely expressing in normal adult tissues, tumors, and cell lines.
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Specifications

Antigen CCDC134
Applications Immunoprecipitation, Western Blot
Classification Recombinant Monoclonal
Clone 026
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene CCDC134
Gene Accession No. Q9H6E4
Gene Alias 2310042L06Rik; AW208859; Ccdc134; coiled-coil domain containing 134; coiled-coil domain-containing protein 134; dJ821D11.3
Gene Symbols CCDC134
Host Species Rabbit
Immunogen Recombinant Human CCDC134 protein (Met1-Leu229).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79879
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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