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Invitrogen™ CCDC14 Polyclonal Antibody
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Catalog No. PIPA557211
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100 μL
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PIPA557211 100 μL
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Catalog No. PIPA557211 Supplier Invitrogen™ Supplier No. PA557211
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TCTDVLRNSF NTSPGVPCSL PKTDISAIPT LQQLGLVNGI LPQQGIHKET DLLKCIQTYL SLFRSHGKET HLDSQTHRSP TQSQPAFLA Highest antigen sequence identity to the following orthologs: Mouse - 52%, Rat - 43%.

CCDC14 (Coiled-Coil Domain-Containing 14) is a gene that encodes a protein involved in ciliary function and cellular division processes. This protein contains coiled-coil domains that facilitate protein-protein interactions crucial for the assembly and stabilization of microtubule structures within the cell. Research indicates that CCDC14 is essential for proper ciliogenesis, the process by which cells form cilia, which are vital for cell motility, fluid movement, and signal transduction. Additionally, studies have revealed its significant role in the regulation of cell cycle progression and cytokinesis. CCDC14 is required for the accurate segregation of chromosomes during cell division, ensuring genomic stability. Mutations or dysregulation of CCDC14 can lead to ciliopathies and other cellular dysfunctions, highlighting its critical role in maintaining normal cellular activities and its potential implications in various diseases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCDC14
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CCDC14
Gene Accession No. Q49A88
Gene Alias CCDC14; coiled-coil domain containing 14; coiled-coil domain-containing protein 14
Gene Symbols CCDC14
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CCDC14. Recombinant protein control fragment (Product #RP-96446).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64770
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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