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Invitrogen™ CCDC141 Polyclonal Antibody
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Catalog No. PIPA5116237
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400 μL
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PIPA5116237 400 μL
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Catalog No. PIPA5116237 Supplier Invitrogen™ Supplier No. PA5116237
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Description

Rabbit Polyclonal Antibody

CCDC141 Polyclonal Antibody for Western Blot

Coiled-coil domain-containing protein 141 (CCDC141), also known as CAMDI, is a recently identified disrupted in schizophrenia 1 (DISC1)-binding protein that also associates with myosin II. CCDC141 preferentially associates with phosphomyosin II and causes an accumulation of phosphomyosin II at the centrosome in a DISC1-dependent manner. Knockdown of CCDC141 expression by RNAi led to severely impaired radial migration with disoriented chromosomes, suggesting that CCDC141 is required for radial migration through DISC1 and myosin II-mediated centrosome positioning during neuronal development.
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Specifications

Antigen CCDC141
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene CCDC141
Gene Accession No. Q6ZP82
Gene Alias 2610301F02Rik; CAMDI; CCDC141; coiled-coil domain containing 141; coiled-coil domain-containing protein 141; Coiled-coil protein associated with myosin II and DISC1; ENSMUSG00000075261
Gene Symbols CCDC141
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CCDC141.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 285025
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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