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Invitrogen™ CCDC141 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116237

Catalog No. PIPA5116237


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Description

Description

CCDC141 Polyclonal Antibody for Western Blot

Coiled-coil domain-containing protein 141 (CCDC141), also known as CAMDI, is a recently identified disrupted in schizophrenia 1 (DISC1)-binding protein that also associates with myosin II. CCDC141 preferentially associates with phosphomyosin II and causes an accumulation of phosphomyosin II at the centrosome in a DISC1-dependent manner. Knockdown of CCDC141 expression by RNAi led to severely impaired radial migration with disoriented chromosomes, suggesting that CCDC141 is required for radial migration through DISC1 and myosin II-mediated centrosome positioning during neuronal development.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CCDC141
Polyclonal
Unconjugated
CCDC141
2610301F02Rik; CAMDI; CCDC141; coiled-coil domain containing 141; coiled-coil domain-containing protein 141; Coiled-coil protein associated with myosin II and DISC1; ENSMUSG00000075261
Rabbit
Antigen affinity chromatography, Protein A
RUO
285025
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.4
Q6ZP82
CCDC141
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CCDC141.
400 μL
Primary
Human
Antibody
IgG
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