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Invitrogen™ CCDC141 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5116237
Description
CCDC141 Polyclonal Antibody for Western Blot
Coiled-coil domain-containing protein 141 (CCDC141), also known as CAMDI, is a recently identified disrupted in schizophrenia 1 (DISC1)-binding protein that also associates with myosin II. CCDC141 preferentially associates with phosphomyosin II and causes an accumulation of phosphomyosin II at the centrosome in a DISC1-dependent manner. Knockdown of CCDC141 expression by RNAi led to severely impaired radial migration with disoriented chromosomes, suggesting that CCDC141 is required for radial migration through DISC1 and myosin II-mediated centrosome positioning during neuronal development.
Specifications
CCDC141 | |
Polyclonal | |
Unconjugated | |
CCDC141 | |
2610301F02Rik; CAMDI; CCDC141; coiled-coil domain containing 141; coiled-coil domain-containing protein 141; Coiled-coil protein associated with myosin II and DISC1; ENSMUSG00000075261 | |
Rabbit | |
Antigen affinity chromatography, Protein A | |
RUO | |
285025 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot | |
0.5 mg/mL | |
PBS with 0.09% sodium azide; pH 7.4 | |
Q6ZP82 | |
CCDC141 | |
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CCDC141. | |
400 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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