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Invitrogen™ CCDC155 Polyclonal Antibody
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Catalog No. PIPA554116
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100 μL
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Catalog No. Quantity
PIPA554116 100 μL
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Catalog No. PIPA554116 Supplier Invitrogen™ Supplier No. PA554116
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GLELEEETAF QGALTSRQLP SGCPEAEEPA NLESFGGEDP RPELQATADL LSSLEDLELS NRRLVGENAK LQRSM Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 85%.

As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Required for telomere attachment to nuclear envelope in the prophase of meiosis and for rapid telomere prophase movements implicating a SUN1/2:KASH5 LINC complex in which SUN1 and SUN2 seem to act at least partial redundantly. Required for homolog pairing during meiotic prophase in spermatocytes and probably oocytes. Essential for male and female gametogenesis. Recruits cytoplasmic dynein to telomere attachment sites at the nuclear envelope in spermatocytes. In oocytes is involved in meiotic resumption and spindle formation. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCDC155
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CCDC155
Gene Accession No. Q8N6L0
Gene Alias CCDC155; coiled-coil domain containing 155; coiled-coil domain-containing protein 155; KASH domain containing 5; KASH domain-containing protein 5; KASH5; protein KASH5; Unknown (protein for MGC:134376)
Gene Symbols CCDC155
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CCDC155. Recombinant protein control fragment (Product #RP-91568).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 147872
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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