Invitrogen™ CCDC22 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA551477

Catalog No. PIPA551477

Description

Immunogen sequence: YQNFLYPSEP DLRDLLLFLA ERLPTDASED ADQPAGDSAI LLRAIGSQIR DQLALPWVPP HLRTPKLQHL QGSALQKPFH ASRLVVPELS SRGEPREFQA SPLLLPVPTQ VPQPVGRVA Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 87%.

CCDC22 is a recently identified coiled-coil domain-containing protein that has been shown to bind copines, which are calcium-dependent, membrane-binding proteins that may function in calcium signaling. In rat, CCDC22 has been observed to localize in multiple regions of the brain, including the prefrontal and somatosensory cortex, dentate gyrus and thalamus, and in the ipsilateral motor neurons of the spinal cord after sciatic nerve transection suggesting that it may play a role in neuronal injury response. The human CCDC22 gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability (XLID).

Specifications

• Antigen: CCDC22
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ccdc22
• Gene Alias: AI481216; Ccdc22; ccdc22 {ECO:0000250; coiled-coil domain containing 22; coiled-coil domain-containing protein 22; coiled-coil domain-containing protein 22 {ECO:0000250; CXorf37; DXImx40e; JM1; Ppp1r3f; RGD1560910; RTSC2; Sfc22; UniProtKB:O60826}
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 28952, 317381, 54638
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O60826, P86182, Q9JIG7
• Gene Symbols: Ccdc22
• Immunogen: Recombinant protein corresponding to Human CCDC22. Recombinant protein control fragment (Product #RP-91924).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG