CCDC36 Mouse anti-Human, Clone: OTI2F7, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF808389

Catalog No. 50-166-8818

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.

Specifications

• Antigen: CCDC36
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: CCDC36
• Gene Alias: CT74
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 339834
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI2F7
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q8IYA8
• Gene Symbols: CCDC36
• Immunogen: Full length human recombit protein of human CCDC36 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1